First name: Elaheh
Last name: Amini
Date of birth: 18^th March.1983
Nationality: Iranian
Marital Status: Married
Language: Persian

Email: elah.amini73@gmail.com; elaheh.amini@khu.ac.ir

Affiliation:  Assistant Professor, Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Iran.

 
Academic Background
Bachelor of Biology, Zabol University, Zabol, Iran, 2002-2006.
Master of Cell and Developmental Biology, Tarbiat Molallem University, Iran, 2007-2010.
Ph.D of Cell and Developmental Biology, Kharazmi University, Iran, 2011-2015.
 
 
Awards and Honors

• The Best Student in PhD Course
• The Second Best Student in Master Course

 
Publications
 

1. Kouchesfehani H, Nabiuni M, Majlesara M, Amini E. The Effect of Nd-YAG Laser in Photodynamic Treatment on LN-CaP Cells. Iranian Journal of Animal Biology. 2010; 2 (2):1-8.
 
2. Kouchesfehani H, Nabiuni M, Majlesara MH, Amini E, Irian S.  Effect of vitamin E succinate as a differentiation agent on the efficacy of 5-ALA-PDT on prostate cancer cells in culture. Journal of Paramedical Science, 2011; 2(3): 16-23.
 
3. Parivar K, Nabiuni M, Golestanian N, Amini E. Effect of low frequency electromagnetic fields on the spermatogenesis and blood serum protein of Balb/c mice. Iranian Journal of Cell & Tissue. 2011;2(1):47-56.
 
4. Nabiuni M, Baharara J, Amini E, Jalali H. Determination of apoptotic doses of bee venom on human promyelocytic leukemia cells. Iranian Journal of Cell & Tissue (JCT), 2012; 2(4): 425-433.
 
5. Baharara J, Amini E, Namvar F, Soltani M. The effect of Persian Gulf sea cucumber alcholic extract on  osteogenic and adipodgenic differentiation of rat mesenchymal stem cells. Iranian Journal of Cell & Tissue. 2014; 5(3): 273-280.
 
6. Baharara J, Amini E, Kerachian M, Soltani M. The osteogenic differentiation stimulating activity of sea cucumber methanolic crude extraction on rat bone marrow mesenchymal stem cell. Iranian Journal of Basic Sciences, 2014; 17:626-631.
 
7. Namvar F, Sulaiman HS, Mohamad R, Baharara J, Amini E. Cytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract. International Journal of Nanomedicine. 2014; 9:2479-2488.
 
8. Amini E, Nabiuni M, Baharara J, Parivar K, Asili J. Metastatic inhibitory and radical scavenging
efficacies of the saponin extracted from the brittle star (Ophiocoma erinaceus). Asian Pacific Journal of Cancer Prevention,2015;16(11):4751-4758.
 
9. Mostafapour A, Baharara J, Namvar F, Amini E. Polysaccharide isolated from Ophiocoma erinaceus to inhibits cell growth and induces cellular differentiation and apoptosis in B16F10 melanoma cells. Trends in Life Science, 2015; 3(5):55-57.
 
10. Baharara J, Amini E. The Potential of Brittle Star Extracted Polysaccharide in Promoting Apoptosis via Intrinsic Signaling Pathway. Avicenna Journal of Medical Biotechnology,2015; 7(4): 151-158.
 
11. Baharara J, Amini E, Nikdel N, Afzali M. The pro-apoptotic effect of brittle Star dichloromethane extract on B16F10 melanoma cell line. Journal of Paramedical Science.2015; 6(3):74-80.
 
12. Namvar F, Baharara J, Amini E, Mahdavi M. effect of magnetic iron oxide nanoparticles coated with Seaweed Aqueous Extract against ovarian Cancer Cells. Fyz Journal of Kashan University of Medical Science, 2015; 19(2): 94-101.
 
13. Nikdel N, Baharara J, Shahrokh Abady Kh,Amini E. Cytotoxic effect of sea cucumber body wall extract (Holothuria arenicola) on melanoma cancer cells. Journal of Sharekord Medicine University.2015; 17(5):33-43.
 
14. Baharara J, Amini E, Mousavi M.The anti-proliferative and anti angiogenic effect of brittle star methanol extract. Reports of Biochemistry & Molecular Biology, 2015; 3(2),1-8.  
 
15. Baharara J,Amini E. Phytochemical screening antioxidant effect and down regulation of TGF-B
induced by ophiocoma erinaceus brittle star crude extract. Zahedan Journal of Research in Medical Sciences. 2015; 17(12): e51941.
 
16. Afzali M, Baharara J, Shahrokh Abady Kh, Amini E. Evaluating the effect of Persian Gulf Brittle Star dichloromethane extract in apoptosis induction of EL4 cell line. Journal of Rafsanjan Medicine University.2015; 14(6):467-480.
 
17. Baharara J, Amini E, Salek-abdollahi F, Nikedel N,Asadisamani M. Protective effect of date palm
pollen (Phoenix dactylifera) on sperm parameters and sexual hormones in male NMRI mice exposed to low frequency electromagnetic field (50 Hz).  J HerbMed Pharmacol. 2015; 4(3): 75-80.
 
18. Salek-Abdollahi F, Baharara J, NejadShahrokhabadi Kh, Namvar F, Amini E. Effect of Phoenix dactylifera pollen grain on maturation of preantral follicles in NMRI mice. J HerbMed Pharmacol. 2015; 4(3):93-97
 
19. Amini E, Baharara J, Nikdel N, Salek Abdollahi F. Cytotoxic and Pro-Apoptotic Effects of Honey Bee Venom and Chrysin on Human Ovarian Cancer Cells. Asia Pacific Journal of Medical Toxicology (APJMT) 2015; 4(2): 68-73.
 
20. Vasei N, Baharara J, Zafar Balanezhad S, Amini E. Investigation on the effect of Persian Gulf sea cucumber aqua extract (Holothuria arenicola) in prevention of injuries induced by electromagnetic field (50 Hz) on male gonads in Balb/C mice. 2016; NBR, 2 (3): 216-226.
 
21. Moshfegh F, Baharara J, Namvar F, Zafar-Balanezhad S, Jafarzadeh L, Amini E. Effects of date palm pollen on fertility and development of reproductive system in female Balb/C mice. J HerbMed Pharmacol. 2016; 5(1): 30-35.
 
22. Soheili A, Baharara J, Mahdavi Shahri N, Zafar Balanejad S, Amini E. Protective Effect of the Persian Gulf brittle star Ophiocoma erinaceus extract on carbon tetrachloride (CCl4) induced liver damage in adult male Wistar rat. Birjand Medical Journal. 2016; 22(4): 316-326.
 
23. Baharara J, Amini E, Vazifedan V. Concomitant use of sea cucumber organic extract and radiotherapy on proliferation and apoptosis of Cervical (HeLa) cell line. Zahedan Journal of Research in Medical Sciences, 2016; 18(4):e6442.
 
24. Khalilzadeh M, BahararaJ, Jalali M, Namvar F, Amini E. The sea cucumber body wall extract promoted in vitro maturation of NMRI mice follicles at germinal vesicle stage. Zahedan Journal of Research in Medical Sciences. 2016; 18(8): e3021.
 
25. Sohrabifar N, Baharara J, Mahdavi Shahri N, Zafar Balanejad S and Amini E.  The impact of sheep testis extract on hair follicle growth and skin healing of Wistar rats. Nova Biol. Rep. 2016; 3: 24-38.
 
26. Baharara J, Tayarani Najaran Z, Amini E, Salekabdollahi F. The Inhibitory Effect of Crocin on Melanogenesis of B16F10 Melanoma Cell Line. J Shahid Sadoughi Univ Med Sci, 2016; 24(6): 479-490.
 
27. Baharara J, Amini E, Namvar F. Evaluation of the anti-proliferative effects of Ophiocoma erinaceus methanol extract against human cervical cancer cells. Avicenna Journal of Medical Biotechnology.2016; 8(1): 29-35.
 
28. Kerachian MA, Baharara J, Amini E, Afzali M, Nikdel N, Mostafapour A. Apoptosis inducing capacity of Holothuria arenicola in CT26 colon carcinoma cells in vitro and in vivo. Iranian Journal of Basic Sciences 2016; 19(4):358-365.
 
29. Bahadori M, Baharara J, Amini E. Anticancer properties of chrysin on colon cancer cells, in vitro and in vivo with modulation of caspase-3, -9, Bax and sall4. IJB. 2016; 14(3): 177-184.
 
30.  Baharara J, Amini E, Nikdel Najme, Salek-Abdollahi F. The Cytotoxicity of Dacarbazine Potentiated by Sea Cucumber Saponin in Resistant B16F10 Melanoma Cells Through Apoptosis Induction. Avicenna Journal of Medical Biotechnology. Avicenna Journal of Medical Biotechnology, 2016; 8(3): 112-119.
 
31. Tayarani Z, Baharara J, Amini E. Cytotoxic evaluation of different fractions of Salvia chorassanica Bunge on MCF-7 and DU 145 cell lines. Research in Pharmaceutical Sciences. 2016; 11(1):73-80.
 
32. Delghandi Moghadam F, Baharara J, Zafar Balanezhad S, Jalali M, Amini E. Effect of Holothuria leucospilota extracted saponin on maturation of mice oocyte and granulosa cells. Research in Pharmaceutical Sciences. 2016; 11(2): 130-137.
 
33. Amini E, Nabiuni M, Baharara J, Parivar K, Asili J. In vitro pro apoptotic effect of crude saponin from Ophiocoma erinaceus against cervical cancer. Iranian Journal of Pharmaceutical Research,2017; 16 (1): 266-276.  
 
34. Afzali M, Baharara J, Amini E. Evaluation of the cytotoxic effect of the Brittle Star (Ophiocoma erinaceus) dichloromethane extract and doxorubicin on EL4 cell line. Iranian Journal of Pharmaceutical Research,2017; 16 (Special Issue): 216-226.
 
35. Baharara J, Amini A. Evaluation of the inhibitory synergic effects of Persian Gulf Brittle star extract and taxol on ovarian cancer A2780cp. Iranian Journal of Fisheries Science. 2017; 16(3): 907-919.
 
36. Baharara J, Amini E, Mousavi Marzieh. Anti-Vasculogenic Activity of a Polysaccharide Derived from Brittle Star via Inhibition of VEGF, Paxillin and MMP-9. Iranian J Biotech 2017; 15(3): 179-185.
 
37.  Shakeri A, Amini E, Asili J, Masullo M, Piacente S, Iranshahi M. Screening of several biological activities induced by different sesquiterpene lactones isolated from Centaurea behen L. and Rhaponticum repens (L.) Hidalgo. Natural Product Research 2017; 1-5. http://dx.doi.org/10.1080/14786419.2017.1344661
 
38. Emami SA, Yazdian-Robati R, Sadeghi M, Baharara J, Amini E, Salek, F and Tayarani-Najaran Z. Inhibitory effects of different fractions of Nepeta satureioides on melanin synthesis through reducing oxidative stress. Research in Pharmaceutical Sciences, 2017; 12(2): 160-167.
 
39. Shokri A, Baharara J, Amini E. Evaluation the antioxidant effect of crocin on neonate Balb/C mouse spermatogonial stem cells. Journal of Cell & Tissue, 2017; 7(3):219-229.
 
40. Pordel M, Baharara J, Amini E. Cytotoxic and antioxidant effect of chrysin on neonate mouse spermatogenic stem cells. Feyz, Journal of Kashan University of Medical Sciences, 2017; 21(2): 126-133.
 
41. Hashemi-Shahri SH, Golshan A, Mohajeri SA, Baharara J, Amini E, Salek F, Sahebkar A and Tayarani-Najaran Z. ROS-scavenging and Anti-tyrosinase Properties of Crocetin on B16F10 Murine
Melanoma Cells. Anti-Cancer Agents in Medicinal Chemistry, 2018; 18: 1064-1069.
 
42. Seyfi D, Behzad SB, Nabiuni M, Parivar K, Tahmaseb M, Amini E. Verbascoside Attenuates Rac-1 and HIF-1α Signaling Cascade in Colorectal Cancer Cells. Anticancer Agents Med Chem. 2018; 18(15): 2149-2155.
 
43. Amini E, Nabiuni M, Baharara J, Behzad SB, Seyfi D, Salek F. Investigating the anticancer effect of Lippia citriodora leaf alcoholic extract: in suppression of A2780 ovarian cancer cell metastasis via restoration of E-cadherin expression. Journal of Cell & Tissue 2019; 10(1): 24-33.
 
44. Baharara J, Nikdel N, Shahrokhabadi Kh, Amini E. The synergistic influence of Holothuria arenicola extract and imidazole carboxamide on Cellosaurus cell line B16-F10. Iranian Journal of Fisheries Science.2019; 18(1): 173-187.
 
45. Amini E, Baharara J, Afzali M, Nikedel N. The p53 Modulated Cytotoxicity of Ophiocoma scolopendrina Polysaccharide Against Resistance Ovarian Cancer Cells. Avicenna J Med Biotech 2019; 11(3): 208-214.
 
46. Tayarani-Najaran Z, Yazdian-Robati R, Amini E, Salek F, Arasteh F, Emami SA. The mechanism of neuroprotective effect of Viola odorata against serum/glucose deprivation-induced PC12 cell death. Avicenna J Phytomed, 2019; 9(6): 491-498.
 
47. Baharvand Z, Nabiuni M, Tahmaseb M, Amini E, Pandamooz S. Investigating the synergic effects of valproic acid and crocin on BDNF and GDNF expression in epidermal neural crest stem cells. Acta Neurobiol Exp 2020, 80: 38–46.
 
48. Baharara J, Amini E, Salek F. Anti-inflammatory properties of saponin fraction from (Spiny brittle star) Ophiocoma erinaceus (Müller and Troschel, 1842). Iranian Journal of Fisheries Sciences. 2020; 19(2) 638-652.
 
49. Mehrabifard R,  Mehdian H, Hajisharifi K, Amini E. Improving Cold Atmospheric Pressure Plasma Efficacy on Breast Cancer Cells Control-Ability and Mortality Using Vitamin C and Static Magnetic Field. Plasma Chemistry and Plasma Processing 2020; 40, 511–526.
 
50. Abolhasani, I., Baharara, J., Mahdavi Shahri, N. & Amini, E. The regenerative properties of the extracted polysaccharide from Brittle star (Ophiocoma erinaceus) on cutaneous wound in male Wistar rat. Nova Biologica Reperta 2020; 7: 9-18.
 
51. Khodabandeh Shahraki F, Nabiuni M, Farhadi M, Amini E. The Effect of Hydroalcoholic Rosmarinus Officinalis (Rosemary) on Memory Retention Deficit in Young Offspring Rat Induced by Maternal Sleep Deprivation. Pharmaceutical and Biomedical Research. 2020; 6(2):157-168.
 
52. Amini E, Nabiuni M, Behzad SB, Seyfi D, Eisvand F, Sahebkar A, Shakeri A. Anticancer Potential of Aguerin B, a Sesquiterpene Lactone Isolated from Centaurea behen in Metastatic Breast Cancer Cells. Recent Patents on Anti-Cancer Drug Discovery, 2020, 15, 1-09.

 
 
 Congress Full paper
 

1. Mostafapour A, Baharara J, Amini E. Effects of dichloromethane extract from Brittle star (Ophiocoma erinaceus) on differentiation of B16F10 melanoma cell. 3^th International Conference on Advances in Engineering and Basic science. London. (Poster presentation, published full article)
 
2. Salek_Abdollahi F, Baharara J, Nikdel N, Amini E. Anti-metastatic effect of Polysaccharide Extracted from Brittle star Ophiocoma erinaceus on human cervical cancer cells in vitro. International congress of Nastaran Symposium.(published full article in Journal of Cellular Immunology)
 
3. Amini E, Niknejad A. The effect of walnut green husk hydroalcoholic extract on differentiation of melanoma cell line B16F10. 3^rd International and 11^th National Biotechnology Congress of Islamic Republic of Iran.

 
Congress Abstracts
 

1- Amini E, Kouchesfehani H, Nabiuni M, Majlesara M. The Effect of 5-ALA and Nd-YAG Laser on LN-CaP prostate cancer cells. The 16^th congress of optic & photonic.(Oral presentation)  
 
2- Amini E, Nabiuni M, Baharara J, Parivar K, Asili J. Antioxidant effect of saponin extracted from Persian Gulf Brittle star(Ophiocoma erinaceus). 18th national and 6th International Congress of Biology in Iran.(Oral presentation)
 
3- Amini E, Kouchesfehani H, Nabiuni M, Majlesara M. Differentiation and photodynamic therapy on prostate cancer cells. The 16^thnational and 4^thinternational conference of biology.(Poster presentation)
 
4- Amini E, Kouchesfehani H, Nabiuni M. Differentiation therapy for treatment prostate cancer. The 9^thiranian conference of anatomical science.(Poster presentation)
 
5- Amini E,Baharara J, Nabiuni M.Combination effect of brittle star organic extract and radiotherapy on A2780cp cancer cell growth. The 8^thannual clinical oncology congress.(Poster presentation)
 
6- Amini E,Baharara J, Nabiuni M. Evaluation of cytotoxic effect of sea cucumber methanol extract on B16F10 melanoma cancer cells.International congress on natural product.(Poster presentation)
 
7- Amini E,Baharara J, Nabiuni M. Antiproliferative and antimetastatic activity of brittle star organic extract in human ovarian cancer cells.The 6^th International Congress of Clinical Laboratory and Clinic. (Poster presentation)
 
8- Nabiuni M, Amini E, Jalali H. Determination the type of cell death induced by bee venom in acute promyelocytic HL-60 cancer cells. Iranian congress of applied biology. (Poster presentation)
 
9- Salek_Abdollahi F, Baharara J, Amini E, Nikdel N, Bahadori M. Ophiocoma Erinaceus Extract Stimulate Osteoblast Differentiation in Bone Marrow Mesenchymal Stem Cells. Int congress on stem cells & Regenerative medicine.(Poster presentation)
 
10- Salek_Abdollahi F, Baharara J, Nikdel N, Amini E. Anti-metastatic effect of Polysaccharide Extracted from Brittle star Ophiocoma erinaceus on human cervical cancer cells in vitro. International congress of Nastaran Symposium.(Poster presentation)
 
11- Baharara J, Amini E, Salek_Abdollahi F, Nikdel N, Vasei N. Growth inhibitory and anti-metastatic
effects of brown algae dichloromethane extract on B16F10 melanoma cells. The 8 th APOCP Regional Conference. (Poster presentation)
 
12- Shokri A, Baharara J, Amini E. Evaluation of the protective effect of crocin  on neonate Balb/C mice spermatogonial stem cells. The 8 th International Congress of Laboratory and Clinic. (Poster presentation
 
13. Vasei N, Baharara J, Zafarbalanejad Saeedeh, Amini E. Protective effect of (Holothuria arenicola) against injuries induced by electromagnetic field (50 Hz) on sperm parameters in Balb/C mice. The 8 th Annual Meeting of Reproductive and Fertility updates. (Poster presentation)
 
14. Pordel M, Baharara J, Amini E. Evaluation of the protective effect of chrysin on neonate Balb/C mice spermatogonial stem cells. The 8 th International Congress of Laboratory and Clinic. (Poster presentation)
 
15. Nabiuni M, Amini E, Fathi M. Involvement of   Intrinsic Apoptotic Signaling Pathway In 4T1 Breast            Cancer Cells By Sargassum   Muticum Polysaccharide Fraction. Second    international Nastaran Cancer Symposium (2016) (Poster presentation)
 
16. Behzad SB, Seyfi D, Nabiuni M, Parivar K, Tahmaseb M, Amini E. Involvement of Pak1 gene expression in cytotoxicity of verbascoside on MDA-MB-231 breast cancer cells. 13^th International 
Breast Cancer Congress 2018 (Poster presentation)
 
17. Seyfi D, Behzad SB, Nabiuni M, Parivar K, Tahmaseb M, Amini E. The effect of verbascoside on HIF-1α expression as valuable metastasis and angiogenesis factor in HT-29 colon cancer cells. 13^th International  Breast Cancer Congress 2018 (Poster presentation)
 
18. Shahsavand Inanloo O, Mohseni Kouchesfehani H, Parivar K, Amini E. The Effect of Allogeneic Mouse Serum, Fetal Bovine Serum and Bovine Serum Albumin on Sperm Capacitation. The 4^th International Congress on Reproduction (ISERB 2018) (Poster presentation)
 
19. Khodabandeh Shahraki F, Nabiuni M, Farhadi M, Amini E. The effect of rosemary extract on memory retention deficit in young offspring induced by maternal sleep deprivation in Rat model. International  Congress on the New Aspects of Applied Biology (2018). (Oral presentation)
 
20. Shahsavand Inanloo O, Mohseni kouchesfahani H, Parivar K, Amini E, Hadi M. In vitro maturation and fertilization in mice NMRI: Comparison of the effect of bovine serum albumin, fetal bovine serum, autologous and allogeneic mice serums. International Congress on the New Aspects of Applied Biology (2018). (Oral presentation)
 
21. Ahmadi Sh, Nabiuni M, Tahmaseb M, Amini E. Investigating the effect of lithium on differentiation of epidermal neural crest stem cell into neural cells. 3^rd International Neuroinflammation Congress and 3^rd International Student Festival of Neuroscience. (2018). (Poster presentation)
 
22. Kouchaki R, Nabiuni M, Amini E. Antimetastatic effect of Quillaja saponin in SKOV3 and A2780 human cell lines. 3^rd  International congress on Biomedicine. (2019) (Poster presentation)
 
23. Paktinat O, Nabiuni M, Amini E. Assessment the potential of date palm pollen extract on mice granulosa cell viability. 12^th International congress of Medical lab and clinic (2019) (Poster presentation)
 
24. Fallah Hosseini N, Nabiuni M, Amini E. Evaluation the effect of crocin as saffron bioactive metabolite on proliferation of mice granulosa cell. 12^th International congress of Medical lab and clinic (2019) (Poster presentation)
 
25. Rahimi F, Nabiuni M, Amini E. How aluminium chloride can impact on granulosa function? 3rd debatable topics on obstetrics gynecology & infertility. (2020) (Poster presentation)

 
 
Workshop
 
1. Isolation and characterization of mice spermatogonial stem cells
2. RT-PCR: Principles & Methods
3. Introduction to cell culture principles
4. Cancer cell culture & treatment Method
5. Basics of cancer cell culture & in vitro assays
6. Essential of Stem cell culture and differentiation
7. Rat bone marrow mesenchymal stem cell isolation and application
8. Mice spermatogonial stem cells: isolation method, culture process and application
 
Book translation
1. Human Embryology and Developmental Biology, Bruce M. Carlson.
2. An Introduction to Molecular Biotechnology: Fundamentals, Methods and Applications, Michael Wink.
 
Training Courses
Cellular Banking
Immunocytochemistry & Flow cytometry
Immunobloting
IVF
Neural progenitor cell culture
 
 
Research Interests
Cancer investigation
Natural products and cancer
Stem Cell Biology
PDT
and Infertility Natural products